Association of Dermatomyositis Sine Dermatitis With Anti-Nuclear Matrix Protein 2 Autoantibodies.

ABSTRACT:

Importance

Reports on dermatomyositis (DM) sine dermatitis (DMSD) are scarce, and the concept of the disease has not been widely accepted.

Objective

To confirm the existence of DMSD, determine its prevalence, and characterize its serologic features.

Design, setting, and participants

This is a cohort study that reviewed clinical information, laboratory data, and muscle pathology slides from January 2009 to August 2019. We further assessed the follow-up data of 14 patients with DMSD. The median (interquartile range) follow-up period was 34 (16-64) months. Muscle biopsy samples, along with clinical information and laboratory data, were sent to a referral center for muscle diseases in Japan for diagnosis. Of patients whose myopathologic diagnosis was made at the National

SUBMITTER: Inoue M 

PROVIDER: S-EPMC7171574 | biostudies-literature | 2020 Jul

REPOSITORIES: biostudies-literature