Acupuncture Improving Early Sexual Development of Girls with Peripheral Precocious Puberty: A Prospective Cohort Study.

ABSTRACT:

Objective

To study primarily on the effect of acupuncture on breast Tanner stage, serum sex hormone level, and TCM symptom scores in girls with peripheral precocious puberty (PPP).

Methods

19 eligible patients diagnosed with PPP received acupuncture intervention for 12 weeks, twice a week for 12 weeks, 24 sessions of acupuncture treatment in all, and then follow-up for 12 weeks. The primary outcome was the change in serum luteinizing hormone (LH) level, follicle-stimulating hormone (FSH) level, and breast Tanner stage at 12-week treatment and 12-week follow-up. Serum estradiol (E2) level and TCM symptom scores were also assessed.

Results

Nineteen patients with peripheral precocious puberty were treated with acupuncture. After the 12-week acupuncture intervention, the

SUBMITTER: Liu L 

PROVIDER: S-EPMC7171614 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature