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Case report of a cystic parathyroidal adenoma with rapid growth induced by cinacalcet.


ABSTRACT:

Background

Primary hyperparathyroidism is a rare condition of disease which can seldomly present as giant retrotrhyroideal cysts, complicating the localization of the adenoma to resect.

Case presentation

A 56-year old female presented with hypercalcaemia of 3.38 mmol/L (2.2-2.65 mmol/L) and a history of breast cancer. A fast growing cystic parathyroidal adenoma was diagnosed by a multimodal approach including comprehensive diagnostic imaging (ultrasonography, scintigraphies, dynamic MRI) and cytopathological investigations after ultrasonography-guided puncture. The patient was cured by surgical extraction of the whole adenoma. In retrospect, the rapid growth was most likely induced by cinacalcet (initially 30 mg/d, later 60 mg/d) therapy which the patient received for few mo

SUBMITTER: Werner C 

PROVIDER: S-EPMC7171747 | biostudies-literature | 2020 Apr

REPOSITORIES: biostudies-literature