Prognostic value of pretreatment platelet counts in lung cancer: a systematic review and meta-analysis.

ABSTRACT:

Background

The prognostic value of elevated pretreatment platelet counts remains controversial in lung cancer patients. We performed the present meta-analysis to determine its precise role in these patients.

Methods

We employed a multiple search strategy in the PubMed, EMBASE and Cochrane Library databases to identify eligible studies. Disease-free survival (DFS)/progression-free survival (PFS)/time to progression (TTP) and overall survival (OS) were used as outcomes with hazard ratios (HRs) and 95% confidence intervals (CIs). Heterogeneity among the studies and publication bias were also evaluated.

Results

A total of 40 studies including 16,696 lung cancer patients were eligible for the analysis. Overall, the pooled analysis showed that compared with normal platelet

SUBMITTER: Yuan Y 

PROVIDER: S-EPMC7171794 | biostudies-literature | 2020 Apr

REPOSITORIES: biostudies-literature