Candidate Biomarkers of Suicide Crisis Syndrome: What to Test Next? A Concept Paper.

ABSTRACT:

Background

There has been increasing interest in both suicide-specific diagnoses within the psychiatric nomenclature and related biomarkers. Because the Suicide Crisis Syndrome-an emotional crescendo of several interrelated symptoms-seems to be promising for the identification of individuals at risk of suicide, the aim of the present paper is to review the putative biological underpinnings of the Suicide Crisis Syndrome symptoms (entrapment, affective disturbance, loss of cognitive control, hyperarousal, social withdrawal).

Methods

A PubMed literature search was performed to identify studies reporting a link between each of the 5 Suicide Crisis Syndrome symptoms and biomarkers previously reported to be associated with suicidal outcomes.

Results

Disturbances in the hyp

SUBMITTER: Calati R 

PROVIDER: S-EPMC7171927 | biostudies-literature | 2020 Apr

REPOSITORIES: biostudies-literature