Transcranial Random Noise Stimulation for the Acute Treatment of Depression: A Randomized Controlled Trial.

ABSTRACT:

Background

Transcranial electrical stimulation has broad potential as a treatment for depression. Transcranial random noise stimulation, which delivers randomly fluctuating current intensities, may have greater cortical excitatory effects compared with other forms of transcranial electrical stimulation. We therefore aimed to investigate the antidepressant efficacy of transcranial random noise stimulation.

Methods

Depressed participants were randomly assigned by computer number generator to receive 20 sessions of either active or sham transcranial random noise stimulation over 4 weeks in a double-blinded, parallel group randomized-controlled trial. Transcranial random noise stimulation was delivered for 30 minutes with a direct current offset of 2 mA and a random noise range

SUBMITTER: Nikolin S 

PROVIDER: S-EPMC7171931 | biostudies-literature | 2020 Apr

REPOSITORIES: biostudies-literature