Radiographic pulmonary vessel volume, lung function and airways disease in the Framingham Heart Study.

ABSTRACT: Radiographic abnormalities of the pulmonary vessels, such as vascular pruning, are common in advanced airways disease, but it is unknown if pulmonary vascular volumes are related to measures of lung health and airways disease in healthier populations.In 2388 participants of the Framingham Heart Study computed tomography (CT) sub-study, we calculated total vessel volumes and the small vessel fraction using automated CT image analysis. We evaluated associations with measures of lung function, airflow obstruction on spirometry and emphysema on CT. We further tested if associations of vascular volumes with lung function were present among those with normal forced expiratory volume in 1 s and forced vital capacity.In fully adjusted linear and logistic models, we found that lower total and small

SUBMITTER: Synn AJ 

PROVIDER: S-EPMC7173739 | biostudies-literature | 2019 Sep

REPOSITORIES: biostudies-literature