Novel approach to visualize the inter-dependencies between maternal sensitization, breast milk immune components and human milk oligosaccharides in the LIFE Child cohort.

ABSTRACT:

Background

Numerous studies have shown that specific components of breast milk, considered separately, are associated with disease status in the mother or the child using univariate analyses. However, very few studies have considered multivariate analysis approaches to evaluate the relationship between multiple breast milk components simultaneously.

Aim

Here we aimed at visualizing breast milk component complex interactions in the context of the allergy status of the mother or the child.

Methods

Milk samples were collected from lactating mothers participating in the Leipziger Forschungszentrum für Zivilisationskrankheiten (LIFE) Child cohort in Leipzig, Germany. A total of 156 breast milk samples, collected at 3 months after birth from mother/infant pairs, were analyz

SUBMITTER: Michel L 

PROVIDER: S-EPMC7173766 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature