Long-term blood pressure trajectories and incident atrial fibrillation in women and men: the Tromso Study.

ABSTRACT:

Aims

To explore sex-specific associations between long-term individual blood pressure (BP) patterns and risk of incident atrial fibrillation (AF) in the general population.

Methods and results

Blood pressure was measured in 8376 women and 7670 men who attended at least two of the three population-based Tromsø Study surveys conducted in 1986-87, 1994-95, and 2001. Participants were followed for incident AF throughout 2013. Latent mixed modelling was used to identify long-term trajectories of systolic BP and hypertension. Cox regression was used to estimate associations between the identified trajectories and incident AF. Elevated systolic BP throughout the exposure period (1986-2001) independently and differentially increased risk of AF in women and men. In women, having elev

SUBMITTER: Sharashova E 

PROVIDER: S-EPMC7174044 | biostudies-literature | 2020 Apr

REPOSITORIES: biostudies-literature