Relationship of Total and Free 25-Hydroxyvitamin D to Biomarkers and Metabolic Indices in Healthy Children.

ABSTRACT:

Context

Vitamin D status is usually assessed by serum total 25-hydroxyvitamin D (t25-OHD). Whether free 25-hydroxyvitamin D measures better correlate with various clinical outcomes is unclear.

Objective

To identify correlations between t25-OHD, calculated and direct measures of free 25-OHD, and to identify associations of these measures with other outcomes in children, across the 6 common GC haplotypes.

Design

Healthy urban-dwelling children underwent measurement of relevant variables.

Setting

Academic medical center.

Participants

The study included 203 healthy, urban-dwelling children, aged 6 months to 10 years, predominantly of Hispanic background and representative of all common GC haplotypes.

Intervention

None.

Main outcome measures

Tot

SUBMITTER: Simpson CA 

PROVIDER: S-EPMC7174047 | biostudies-literature | 2020 Apr

REPOSITORIES: biostudies-literature