Similar prevalence of hepatic steatosis among patients with chronic hepatitis C with and without HIV coinfection.

ABSTRACT: Hepatic steatosis (HS) is frequently observed in HIV-infected patients. It is not known whether HIV infection is an independent risk factor for HS development. We aimed to analyze whether HIV coinfection was associated with a higher frequency of HS in patients with chronic hepatitis C. This was a retrospective cross-sectional study. 574 subjects with chronic hepatitis C virus (HCV) infection were included, 246 (43%) of them coinfected with HIV. All of them underwent transient elastography with controlled attenuation parameter (CAP) measurement. HS was defined as CAP ≥ 248 dB/m. 147 individuals (45%) showed HS in the HCV-monoinfected group and 100 (40.7%) in the HIV/HCV-coinfected group (p = 0.318). HS was associated with body mass index (BMI) [<25 Kg/m² vs. ≥25 Kg/m²,

SUBMITTER: Fernandez-Fuertes M 

PROVIDER: S-EPMC7174281 | biostudies-literature | 2020 Apr

REPOSITORIES: biostudies-literature