Synergism between Corynebacterium and Streptococcus sanguinis reveals new interactions between oral commensals.

ABSTRACT: The oral microbiome engages in a diverse array of highly sophisticated ecological interactions that are crucial for maintaining symbiosis with the host. Streptococci and corynebacteria are among the most abundant oral commensals and their interactions are critical for normal biofilm development. In this study, we discovered that Streptococcus sanguinis specifically responds to the presence of Corynebacterium durum by dramatically altering its chain morphology and improving its overall fitness. By employing gas chromatography-mass spectrometry (GC-MS) analysis, specific fatty acids were identified in C. durum supernatants that are responsible for the observed effect. Membrane vesicles (MVs) containing these fatty acids were isolated from C. durum supernatants and were able to replicate the

SUBMITTER: Treerat P 

PROVIDER: S-EPMC7174362 | biostudies-literature | 2020 May

REPOSITORIES: biostudies-literature