Maternal Thyroid Dysfunction and Gestational Anemia Risk: Meta-Analysis and New Data.

ABSTRACT: Background: Previous studies indicate the effects of thyroid dysfunction on adverse obstetric outcomes and fetal neurodevelopment, of which the results on gestational anemia are controversial. Here, we evaluated the influence of thyroid dysfunction on gestational anemia via published epidemiological articles and a new prospective study conducted by our team, respectively. Methods: We searched studies on the PubMed, Embase, MEDLINE, and Cochrane databases as of November 2019, and conducted a prospective study in which participants underwent thyroid function and blood routine testing throughout pregnancy. Results: The meta-analysis showed that pregnancies with overt hypothyroidism [OH; odds ratio (OR) = 3.74, 95% confidence interval (CI): 1.95-7.15] or that were thyroid

SUBMITTER: Yang Y 

PROVIDER: S-EPMC7174567 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature