Near-Infrared Chemiluminescent Carbon Nanodots and Their Application in Reactive Oxygen Species Bioimaging.

ABSTRACT: Reactive oxygen species (ROS) are generated in the body and related to many pathophysiological processes. Hence, detection of ROS is indispensable in understanding, diagnosis, and treatment of many diseases. Here, near-infrared (NIR) chemiluminescent (CL) carbon nanodots (CDs) are fabricated for the first time and their CL quantum yield can reach 9.98 × 10^-3 einstein mol^-1, which is the highest value ever reported for CDs until now. Nanointegration of NIR CDs and peroxalate (P-CDs) through the bridging effect of amphiphilic triblock copolymer can serve as turn-on probes for the detection and imaging of hydrogen peroxide (H₂O₂). Considering high efficiency and large penetration depth of NIR photons, the P-CDs are employed in bioimaging H₂

SUBMITTER: Shen CL 

PROVIDER: S-EPMC7175254 | biostudies-literature | 2020 Apr

REPOSITORIES: biostudies-literature