Cmfhp Gene Mediates Fruiting Body Development and Carotenoid Production in Cordyceps militaris.

ABSTRACT: Cordyceps militaris fruiting bodies contain a variety of bioactive components that are beneficial to the human body. However, the low yield of fruiting bodies and the low carotenoid content in C. militaris have seriously hindered the development of the C. militaris industry. To elucidate the developmental mechanism of the fruiting bodies of C. militaris and the biosynthesis mechanism of carotenoids, the function of the flavohemoprotein-like Cmfhp gene of C. militaris was identified for the first time. The Cmfhp gene was knocked out by the split-marker method, and the targeted gene deletion mutant ΔCmfhp was obtained. An increased nitric oxide (NO) content, no fruiting body production, decreased carotenoid content, and reduced conid

SUBMITTER: Lou HW 

PROVIDER: S-EPMC7175373 | biostudies-literature | 2020 Mar

REPOSITORIES: biostudies-literature