Reliability assessment for blood oxygen saturation levels measured with optoacoustic imaging.

ABSTRACT:

Significance

Quantitative optoacoustic (OA) imaging has the potential to provide blood oxygen saturation (SO2) estimates due to the proportionality between the measured signal and the blood's absorption coefficient. However, due to the wavelength-dependent attenuation of light in tissue, a spectral correction of the OA signals is required, and a prime challenge is the validation of both the optical characterization of the tissue and the SO2.

Aim

We propose to assess the reliability of SO2 levels retrieved from spectral fitting by measuring the similarity of OA spectra to the fitted blood absorption spectra.

Approach

We introduce a metric that quantifies the trends of blood spectra by assigning a pair of spectral slopes to each spectrum. The applicability of the metric

SUBMITTER: Ulrich L 

PROVIDER: S-EPMC7175414 | biostudies-literature | 2020 Apr

REPOSITORIES: biostudies-literature