Statins for multiple sclerosis.

ABSTRACT:

Background

Multiple sclerosis (MS) is an inflammatory demyelinating disease of the human central nervous system. Statins, prescribed as cholesterol lowering agents, have shown possible effects for treating MS in experimental and preliminary clinical studies.

Objectives

To evaluate the efficacy and safety of statins administered alone or as add-on to approved treatments for MS.

Search methods

The Trials Search Coordinator searched the Cochrane MS Group Trials Register (1 August 2011). We searched the Chinese National Knowledge Infrastructure (CNKI) (1979 to 1 August 2011), trials registers and conference proceedings. Pharmaceutical companies and authors of included studies were contacted for additional information.There were no language restrictions.

Selection crite

SUBMITTER: Wang J 

PROVIDER: S-EPMC7175839 | biostudies-literature | 2011 Dec

REPOSITORIES: biostudies-literature