Surgical and regional treatments for colorectal cancer metastases in older patients: A systematic review and meta-analysis.

ABSTRACT:

Objective

The present study explored the existing literature to describe the outcomes of surgical and regional treatments for colorectal cancer metastases (mCRC) in older patients.

Methods

A literature search was conducted in PubMed, EMBASE, Cochrane and ClinicalTrials.gov for studies published since 2000 that investigated the short- and long-term outcomes of regional treatments (surgical or non-surgical) for mCRC in patients aged ≥65 years. Pooled data analyses were conducted by calculating the risk ratio (RR), mean differences (MD) and hazard ratio (HR) between older and younger patients or between two different approaches in older patients.

Results

After screening 266 articles, 29 were included in this review. These studies reported the outcomes of surgery (n = 19)

SUBMITTER: de'Angelis N 

PROVIDER: S-EPMC7176093 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature