Dataset Information

Bleeding Complications in Lower-Extremity Peripheral Vascular Interventions: Insights From the NCDR PVI Registry.

ABSTRACT:

Objectives

This study sought to assess periprocedural bleeding complications in lower-extremity peripheral vascular interventions (PVIs).

Background

Few studies have examined the incidence, predictors, or outcomes of periprocedural bleeding after lower-extremity PVI.

Methods

The study examined patients undergoing PVI at 76 hospitals in the National Cardiovascular Data Registry PVI registry from 2014 to 2016. Post-PVI major bleeding was defined as any overt bleeding with a hemoglobin (Hb) drop of ≥3 g/dl, any Hb decline of ≥4 g/dl, or blood transfusion in patients with pre-procedure Hb >8 g/dl within 72 h of their procedure. Hierarchical multivariable logistic regression was used to identify factors independently associated with post-PVI bleeding. The study also examined adjusted in-hospital mortality among patients with or without major bleeding complications.

Results

Among 18,289 PVI procedures, major bleeding occurred in 744 (4.10%). Patient characteristics independently associated with bleeding included age, female sex, heart failure, pre-procedural hemoglobin <12 g/dl, nonelective PVI, and critical limb ischemia on presentation. Procedural characteristics associated with bleeding included nonfemoral vascular access, use of thrombolytic therapy, PVI of the aortoiliac segment, and multilesion interventions, whereas use of closure devices was associated with less bleeding. All-cause in-hospital mortality was higher in patients who experienced bleeding than in those who did not (6.60% vs. 0.30%; p < 0.001; adjusted hazard ratio: 10.9; 95% confidence interval: 6.9 to 17.0).

Conclusions

Major bleeding occurred in 4.10% of lower-extremity PVI procedures and was associated with several patient and procedural characteristics, as well as in-hospital mortality. These insights can be incorporated into strategies to reduce periprocedural bleeding after PVI.

SUBMITTER: Bhardwaj B

PROVIDER: S-EPMC7176493 | biostudies-literature | 2019 Jun

REPOSITORIES: biostudies-literature

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Publications

Bleeding Complications in Lower-Extremity Peripheral Vascular Interventions: Insights From the NCDR PVI Registry.

Bhardwaj Bhaskar B Spertus John A JA Kennedy Kevin F KF Jones W Schuyler WS Safley David D Tsai Thomas T TT Aronow Herbert D HD Vora Amit N AN Pokharel Yashashwi Y Kumar Arun A Attaran Robert R RR Feldman Dmitriy N DN Armstrong Ehrin E Prasad Anand A Gray Bruce B Salisbury Adam C AC

JACC. Cardiovascular interventions 20190601 12

<h4>Objectives</h4>This study sought to assess periprocedural bleeding complications in lower-extremity peripheral vascular interventions (PVIs).<h4>Background</h4>Few studies have examined the incidence, predictors, or outcomes of periprocedural bleeding after lower-extremity PVI.<h4>Methods</h4>The study examined patients undergoing PVI at 76 hospitals in the National Cardiovascular Data Registry PVI registry from 2014 to 2016. Post-PVI major bleeding was defined as any overt bleeding with a h ...[more]

PMID: 31221303

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Dataset Information

Bleeding Complications in Lower-Extremity Peripheral Vascular Interventions: Insights From the NCDR PVI Registry.

Objectives

Background

Methods

Results

Conclusions

Publications

Bleeding Complications in Lower-Extremity Peripheral Vascular Interventions: Insights From the NCDR PVI Registry.

Similar Datasets

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