Efficient synthesis of dipeptide analogues of α-fluorinated β-aminophosphonates.

ABSTRACT: Herein, we present an efficient synthesis of dipeptide analogues of α-fluorinated β-aminophosphonates. Each step of the synthesis was optimized to provide excellent yields. Moreover, the absolute configuration of the obtained compounds was determined by X-ray analysis, which proved the stereochemistry that was proposed based on NMR studies.

SUBMITTER: Kazmierczak M 

PROVIDER: S-EPMC7176923 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature