Ontology highlight
ABSTRACT:
SUBMITTER: Semba T
PROVIDER: S-EPMC7177258 | biostudies-literature | 2020 Apr
REPOSITORIES: biostudies-literature
International journal of molecular sciences 20200409 7
C-JUN N-terminal kinases (JNKs), which belong to the mitogen-activated protein kinase (MAPK) family, are evolutionarily conserved kinases that mediate cell responses to various types of extracellular stress insults. They regulate physiological processes such as embryonic development and tissue regeneration, playing roles in cell proliferation and programmed cell death. JNK signaling is also involved in tumorigenesis and progression of several types of malignancies. Recent studies have shown that ...[more]