Ontology highlight
ABSTRACT:
SUBMITTER: Di Filippo ES
PROVIDER: S-EPMC7177401 | biostudies-literature | 2020 Apr
REPOSITORIES: biostudies-literature
International journal of molecular sciences 20200405 7
Skeletal muscle differentiation is triggered by a unique family of myogenic basic helix-loop-helix transcription factors, including MyoD, MRF-4, Myf-5, and Myogenin. These transcription factors bind promoters and distant regulatory regions, including E-box elements, of genes whose expression is restricted to muscle cells. Other E-box binding zinc finger proteins target the same DNA response elements, however, their function in muscle development and regeneration is still unknown. Here, we show t ...[more]