An In Vitro Evaluation of the Red Cell Damage and Hemocompatibility of Different Central Venous Catheters.

ABSTRACT:

Background

The aim of our study was to evaluate the damaging impact of characteristics of the central venous catheters (CVCs) on red blood cells.

Methods

CVCs from three different manufacturers were analyzed, including the presence of coating, tunnel geometry, length, lumen diameter, and number of lumens with two respective flow rates (33 mL/min and 500 mL/min). Blood cell damage was defined by analyzing microparticle (MP) and hematologic analysis. MPs were isolated by ultracentrifugation of erythrocyte concentrate and analyzed on a flow cytometer.

Results

Characteristics of catheters were not associated with blood cell damage at a low flow rate but showed an effect with a high flow rate. CVCs with a polyhexanide methacrylate coating have caused statistically less blo

SUBMITTER: Ihan A 

PROVIDER: S-EPMC7178527 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature