Antimicrobials administration time in patients with suspected sepsis: is faster better? An analysis by propensity score.

ABSTRACT:

Background

Early use of antimicrobials is a critical intervention in the treatment of patients with sepsis. The exact time of initiation is controversial and its early administration may be a difficult task in crowded emergency departments (ED). The aim of this study was to estimate, using a matched propensity score, the effect on hospital mortality of administration of antimicrobials within 1 or 3 hours, in patients admitted to the ED with sepsis.

Methods

This was a secondary analysis of a multicenter prospective cohort. Patients included in the study were older than 18 years, hospitalized between 2014 and 2016 with suspected sepsis, and admitted to ED of three tertiary care university hospitals in Medellín, Colombia. A propensity score analysis for administration of antimi

SUBMITTER: Ascuntar J 

PROVIDER: S-EPMC7178597 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature