A multi-country, multi-year, meta-analytic evaluation of the sex differences in age-specific pertussis incidence rates.

ABSTRACT:

Background

Pertussis is frequently reported to be more common in females than in males. However, the variability of the sources of these observations makes it difficult to estimate the magnitude and consistency of the sex differences by age. To address this question, we used meta-analytic methods to analyze pertussis national incidence rates by sex and age group from nine countries between the years 1990 and 2017.

Methods

For each age group, we used meta-analytic methods to combine the female to male incidence rate ratios (RRs) by country and year. Meta-regression was performed to assess the relative contributions of age, country and time-period to the variation in the incidence RRs.

Results

The pooled female to male incidence RRs (with 95% CI) for ages 0-1, 1-4, 5-9

SUBMITTER: Peer V 

PROVIDER: S-EPMC7179848 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature