Does surgically resected small-cell lung cancer without lymph node involvement benefit from prophylactic cranial irradiation?

ABSTRACT:

Background

It has previously been demonstrated that surgically resected small-cell lung cancer (SCLC) patients could benefit from prophylactic cranial irradiation (PCI). However, PCI in patients without lymph node involvement remains controversial. This study includes a larger sample size to evaluate the benefit of PCI therapy in this specific population.

Methods

The records of surgically resected SCLC patients without lymph node involvement (N0M0) in Shanghai Chest Hospital were retrospectively reviewed.

Results

Between January 2006 and May 2017, a total of 146 cases of surgically resected SCLC without lymph node involvement were included. A total of 46 patients received PCI therapy and 100 patients received no therapy. During the observation period, 12.0% (12/100) o

SUBMITTER: Lou Y 

PROVIDER: S-EPMC7180625 | biostudies-literature | 2020 May

REPOSITORIES: biostudies-literature