Racial/ethnic differences in the burden of type 2 diabetes over the life course: a focus on the USA and India.

ABSTRACT: Type 2 diabetes is a common disease worldwide, but its prevalence varies widely by geographical region and by race/ethnicity. This review summarises differences in the frequencies of type 2 diabetes according to race, ethnicity, socioeconomic position, area of residence and environmental toxins. Type 2 diabetes susceptibility often begins early in life, starting with genetic susceptibility at conception and continuing in later life, via in utero, childhood and adult exposures. Early-life factors may lead to overt type 2 diabetes in childhood or in later life, supporting the concept of developmental origins of health and disease. The causes of the racial/ethnic differences in incidence of type 2 diabetes are not well understood. Specifically, the relative contributions of genetic and enviro

SUBMITTER: Golden SH 

PROVIDER: S-EPMC7181870 | biostudies-literature | 2019 Oct

REPOSITORIES: biostudies-literature