Serologic Detection of Middle East Respiratory Syndrome Coronavirus Functional Antibodies.

ABSTRACT: We developed and validated 2 species-independent protein-based assays to detect Middle East respiratory syndrome coronavirus functional antibodies that can block virus receptor-binding or sialic acid-attachment. Antibody levels measured in both assays correlated strongly with virus-neutralizing antibody titers, proving their use for serologic confirmatory diagnosis of Middle East respiratory syndrome.

SUBMITTER: Okba NMA 

PROVIDER: S-EPMC7181916 | biostudies-literature | 2020 May

REPOSITORIES: biostudies-literature