Intraseason Waning of Influenza Vaccine Effectiveness.

ABSTRACT:

Background

In the United States, it is recommended that healthcare providers offer influenza vaccination by October, if possible. However, if the vaccine's effectiveness soon begins to wane, the optimal time for vaccination may be somewhat later. We examined whether the effectiveness of influenza vaccine wanes during the influenza season with increasing time since vaccination.

Methods

We identified persons who were vaccinated with inactivated influenza vaccine from 1 September 2010 to 31 March 2017 and who were subsequently tested for influenza and respiratory syncytial virus (RSV) by a polymerase chain reaction test. Test-confirmed influenza was the primary outcome and days-since-vaccination was the predictor of interest in conditional logistic regression. Models were adjus

SUBMITTER: Ray GT 

PROVIDER: S-EPMC7182205 | biostudies-literature | 2019 May

REPOSITORIES: biostudies-literature