Exposure to air pollution and cognitive impairment risk: a meta-analysis of longitudinal cohort studies with dose-response analysis.

ABSTRACT:

Background

We conducted a meta-analysis to explore the relationship between exposure to air pollution and the risk of cognitive impairment of longitudinal cohort studies.

Methods

PubMed, Web of Science and Wan Fang databases were searched for relevant articles of longitudinal cohort studies published between January 1950 and September 2019. The pooled relative ratio (RR) and 95% confidence interval (CI) were calculated using the random effect model.

Results

Ten articles involving 519 247 cases among 12 523 553 participants were included in this meta-analysis. The pooled RR of cognitive impairment per 5 μg/m³ increments in exposure to particulate matter ≤2.5 μm (PM_2.5) was 1.08 (95% CI = 1.03, 1.13; I²  = 82.2%; P_heteroge

SUBMITTER: Yu X 

PROVIDER: S-EPMC7182361 | biostudies-literature | 2020 Jun

REPOSITORIES: biostudies-literature