Validation and Assessment of the COPD Treatment Ratio as a Predictor of Severe Exacerbations.

ABSTRACT:

Background

Population-based risk assessments are needed to identify individuals who may benefit from chronic obstructive pulmonary disease (COPD) management programs for preventing exacerbations. This study compared the validated COPD treatment ratio (CTR) versus other COPD exacerbation predictors: prior exacerbation and rescue and maintenance medication use.

Methods

A retrospective observational study using medical and pharmacy claims data among Medicare Advantage with Part D beneficiaries with COPD (January 2011-August 2016). Unadjusted and adjusted logistic regression models tested the predictive performance (C-statistic) of potential exacerbation predictors for future severe exacerbations.

Results

The unadjusted association between exacerbation predictors and seve

SUBMITTER: Stanford RH 

PROVIDER: S-EPMC7182384 | biostudies-literature | 2020 Jan

REPOSITORIES: biostudies-literature