Association of Nongenetic Factors With Breast Cancer Risk in Genetically Predisposed Groups of Women in the UK Biobank Cohort.

ABSTRACT:

Importance

The association between noninherited factors, including lifestyle factors, and the risk of breast cancer (BC) in women and the association between BC and genetic makeup are only partly characterized. A study using data on current genetic stratification may help in the characterization.

Objective

To examine the association between healthier lifestyle habits and BC risk in genetically predisposed groups.

Design, setting, and participants

Data from UK Biobank, a prospective cohort comprising 2728 patients with BC and 88 489 women without BC, were analyzed. The data set used for the analysis was closed on March 31, 2019. The analysis was restricted to postmenopausal white women. Classification of healthy lifestyle was based on Cancer Research UK guidance (healt

SUBMITTER: Al Ajmi K 

PROVIDER: S-EPMC7182796 | biostudies-literature | 2020 Apr

REPOSITORIES: biostudies-literature