Oncologic oocyte cryopreservation: national comparison of fertility preservation between women with and without cancer.

ABSTRACT:

Purpose

The majority of data regarding oocyte cryopreservation (OC) outcomes focuses on healthy women. We compare trends, cycle characteristics, and outcomes between women freezing oocytes for fertility preservation due to cancer versus elective and other medical or fertility-related diagnoses.

Methods

Retrospective cohort using national surveillance data includes all autologous OC cycles between 2012 and 2016. Cycles were divided into 4 distinct groups: cancer, elective, infertility, and medically indicated. We calculated trends and compared cycle and outcome characteristics between the 4 groups. We used multivariable log-binomial models to estimate associations between indication and gonadotropin dose, hyperstimulation, and cancelation and used Poisson regression models to

SUBMITTER: Kawwass JF 

PROVIDER: S-EPMC7183023 | biostudies-literature | 2020 Apr

REPOSITORIES: biostudies-literature