The fertility willingness and acceptability of preimplantation genetic testing in Chinese patients with autosomal dominant polycystic kidney disease.

ABSTRACT:

Background

With the development and progression of genetic technology, preimplantation genetic testing (PGT) has made it possible to block the inheritance of autosomal dominant polycystic kidney disease (ADPKD) as early as possible. However, we need to know the patients' fertility intentions and their acceptance of PGT.

Methods

A questionnaire survey was conducted to collect data on the basic demographic data, quality of life, social support, fertility willingness, and level of understanding of genetic testing for blocking the inheritance of ADPKD among patients aged 18-45 years in seven hospitals from January 2018 to December 2018. After verification, statistics were calculated.

Results

A total of 260 patients with ADPKD were interviewed, including 137males (52.7%) a

SUBMITTER: Sun M 

PROVIDER: S-EPMC7183678 | biostudies-literature | 2020 Apr

REPOSITORIES: biostudies-literature