Novel reliability criteria for controlled attenuation parameter assessments for non-invasive evaluation of hepatic steatosis.

ABSTRACT:

Background

There is conflicting evidence regarding reliability criteria for the controlled attenuation parameter (CAP; a marker for hepatic steatosis [HS]). Thus, we assessed the diagnostic performance of CAP according to different reliability criteria based on real-world data from an academic centre.

Methods

Patients undergoing measurement of CAP and liver biopsy (±6 months) at the Medical University of Vienna were included. HS was assessed according to SAF score.

Results

In total 319 patients were included. The main aetiologies were non-alcoholic fatty liver disease (NAFLD, n = 177, 55.5%), viral hepatitis (n = 49, 15.4%), and alcoholic liver disease (ALD, n = 29, 9.1%). Histological steatosis and fibrosis stages were: S0: 93 (29.2%), S1: 100 (3

SUBMITTER: Semmler G 

PROVIDER: S-EPMC7184665 | biostudies-literature | 2020 Apr

REPOSITORIES: biostudies-literature