Targeted delivery of nanomaterials with chemical cargoes in plants enabled by a biorecognition motif.

ABSTRACT: Current approaches for nanomaterial delivery in plants are unable to target specific subcellular compartments with high precision, limiting our ability to engineer plant function. We demonstrate a nanoscale platform that targets and delivers nanomaterials with biochemicals to plant photosynthetic organelles (chloroplasts) using a guiding peptide recognition motif. Quantum dot (QD) fluorescence emission in a low background window allows confocal microscopy imaging and quantitative detection by elemental analysis in plant cells and organelles. QD functionalization with β-cyclodextrin molecular baskets enables loading and delivery of diverse chemicals, and nanoparticle coating with a rationally designed and conserved guiding peptide targets their delivery to chloroplasts. Peptide biorecogniti

SUBMITTER: Santana I 

PROVIDER: S-EPMC7184762 | biostudies-literature | 2020 Apr

REPOSITORIES: biostudies-literature