Bacterial target-specific photocatalyst for the enhancement of antibacterial property to targets.

ABSTRACT: A bacterial target-specific titanium oxide (TiO₂) photocatalyst was developed for the enhancement of selective inactivation of targeted bacteria. An antibacterial composition comprising TiO₂ particles immobilized with a bacterial-specific antibody having affinity to bacteria of interest was prepared via a carbodiimide hydrochloride/N-hydroxysulfosuccinimide (EDC/NHS) coupling reaction between polyacrylic acid (PAA) coated TiO₂ and an antibody. As a model case, an antibody to Escherichia coli was conjugated with the PAA-coated TiO₂ (TiO₂-Ab_E). We evaluated the enhancement of the antibacterial effect of TiO₂-Ab_E against target E. coli, compared with its effect on other bacteria that lack aff

SUBMITTER: Song MY 

PROVIDER: S-EPMC7185639 | biostudies-literature | 2014 Apr

REPOSITORIES: biostudies-literature