Respiratory viral coinfection and disease severity in children: A systematic review and meta-analysis.

ABSTRACT:

Background

With advent of molecular diagnostic technologies, studies have reported detection of two or more respiratory viruses in about 30% of children with respiratory infections. However, prognostic role of coinfection remains unclear.

Objective

Evaluate relation between respiratory viral confection and illness severity in children.

Study design

MEDLINE (through PUBMED), EMBASE, EBSCO, LILACS databases were searched up to March 2015 by two independent reviewers. Studies assessing severity of viral coinfection in patients aged less than 18 years were included. Standardized forms were used for data extraction of population, study design, clinical syndromes, virus combinations compared and severity outcomes. Risk of bias and quality of evidence were assessed through E

SUBMITTER: Scotta MC 

PROVIDER: S-EPMC7185664 | biostudies-literature | 2016 Jul

REPOSITORIES: biostudies-literature