Long-term patient-reported distress in locally advanced cervical cancer patients treated with definitive chemoradiation.

ABSTRACT:

Background and purpose

To evaluate longitudinal patient-reported distress in cervical cancer patients treated with definitive chemoradiation (CRT).

Materials and methods

Between 2011 and 2016, consenting cervical cancer patients treated with definitive CRT who completed ≥ 2 revised Edmonton Symptom Assessment System (ESAS-r) questionnaires at clinical visits, including baseline, were included. A linear mixed model was used to assess the longitudinal trend in ESAS-r. A minimal clinically important difference (MCID) for total ESAS-r score was defined as a change of 3-points for improvement and 4-points for deterioration. The proportion of patients with an MCID over time was described using moving averages. To test for changes, mixed effects logistic models were fitted, each of

SUBMITTER: Conway JL 

PROVIDER: S-EPMC7186264 | biostudies-literature | 2020 Jul

REPOSITORIES: biostudies-literature