Immunoendocrine Peripheral Effects Induced by Atypical Antipsychotics.

ABSTRACT: Atypical antipsychotics (AAP) or second-generation antipsychotics are the clinical option for schizophrenia treatment during acute psychoses, but they are also indicated for maintenance during lifetime, even though they are being used for other psychiatric conditions in clinical practice such as affective disorders and autism spectrum disorder, among others. These drugs are differentiated from typical antipsychotics based on their clinical profile and are a better choice because they cause fewer side effects regarding extrapyramidal symptoms (EPS). Even though they provide clear therapeutic benefits, AAP induce peripheral effects that trigger phenotypic, functional, and systemic changes outside the Central Nervous System (CNS). Metabolic disease is frequently associated with AAP and signif

SUBMITTER: Alvarez-Herrera S 

PROVIDER: S-EPMC7186385 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature