Comparison of creatinine-based equations for estimating glomerular filtration rate in deceased donor renal transplant recipients.

ABSTRACT:

Background

Estimating glomerular filtration rate (GFR) is important for clinical management in kidney transplantation recipients (KTR). However, very few studies have evaluated the performance of the new GFR estimating equations (Lund-Malmö Revised-LMR, and Full Age Spectrum-FAS) in KTR.

Methods

GFR was estimated (eGFR) using CKD-EPI, MDRD, LMR, and FAS equations and compared to GFR measurement (mGFR) by reference methods (inuline urinary and iohexol plasma clearance) in 395 deceased-donor KTR without corticosteroids. The equations performance was assessed using bias (mean difference of eGFR and mGFR), precision (standard deviation of the difference), accuracy (concordance correlation coefficient-CCC), and agreements (total deviation index-TDI). The area under receiver opera

SUBMITTER: Selistre LDS 

PROVIDER: S-EPMC7188287 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature