Comparison of IV Insulin Dosing Strategies for Hyperkalemia in the Emergency Department.

ABSTRACT: The objectives of this study were to evaluate the safety and efficacy of insulin dosing of less than 10 units versus 10 units in patients receiving hyperkalemia treatment.

Design

Retrospective single-center study.

Setting

Emergency department at a large academic medical center in the United States.

Patients

Seven hundred adults treated for hyperkalemia with IV regular insulin between April 1, 2013, and September 27, 2018.

Interventions

Patients that received less than 10 units of insulin were compared to those that received 10 units of insulin.

Measurements and main results

Patients treated with less than 10 units had significantly lower frequency of hypoglycemia (11.2% vs 17.6%; p = 0.008). Reduction in serum potassium was significantly more modes

SUBMITTER: Moussavi K 

PROVIDER: S-EPMC7188424 | biostudies-literature | 2020 Apr

REPOSITORIES: biostudies-literature