In vivo large-scale analysis of Drosophila neuronal calcium traces by automated tracking of single somata.

ABSTRACT: How does the concerted activity of neuronal populations shape behavior? Impediments to address this question are primarily due to critical experimental barriers. An integrated perspective on large scale neural information processing requires an in vivo approach that can combine the advantages of exhaustively observing all neurons dedicated to a given type of stimulus, and simultaneously achieve a resolution that is precise enough to capture individual neuron activity. Current experimental data from in vivo observations are either restricted to a small fraction of the total number of neurons, or are based on larger brain volumes but at a low spatial and temporal resolution. Consequently, fundamental questions as to how sensory information is represented on a population scale remain unanswer

SUBMITTER: Delestro F 

PROVIDER: S-EPMC7188892 | biostudies-literature | 2020 Apr

REPOSITORIES: biostudies-literature