Copeptin as a marker of outcome after cardiac arrest: a sub-study of the TTM trial.

ABSTRACT:

Background

Arginine vasopressin has complex actions in critically ill patients, involving vasoregulatory status, plasma volume, and cortisol levels. Copeptin, a surrogate marker for arginine vasopressin, has shown promising prognostic features in small observational studies and is used clinically for early rule out of acute coronary syndrome. The objective of this study was to explore the association between early measurements of copeptin, circulatory status, and short-term survival after out-of-hospital cardiac arrest.

Methods

Serial blood samples were collected at 24, 48, and 72 h as part of the target temperature management at 33 °C versus 36 °C after cardiac arrest trial, an international multicenter randomized trial where unconscious survivors after out-of-hospital card

SUBMITTER: During J 

PROVIDER: S-EPMC7189642 | biostudies-literature | 2020 Apr

REPOSITORIES: biostudies-literature