Lateral semi-circular canal asymmetry in females with idiopathic scoliosis.

ABSTRACT:

Purpose

Adolescent idiopathic scoliosis (AIS) is a three-dimensional spinal structural deformity that occurs in otherwise normal individuals. Although curve progression and severity vary amongst individuals, AIS can lead to significant cosmetic and functional deformity. AIS etiology has been determined to be genetic, however, exact genetic and biological processes underlying this disorder remain unknown. Vestibular structure and function have potentially been related to the etiopathogenesis of AIS. Here, we aimed to characterize the anatomy of the semicircular canals (SCC) within the vestibular system through a novel approach utilizing T2-weighted magnetic resonance images (MRI).

Methods

Three dimensional, MRI-based models of the SCCs were generated from AIS subjects (n = 20

SUBMITTER: Carry PM 

PROVIDER: S-EPMC7190182 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature