Factors Associated with Endocrine Therapy Non-Adherence in Breast Cancer Survivors.

ABSTRACT:

Background

For women with hormone receptor positive breast cancer, long-term endocrine therapy (ET) can greatly reduce the risk of recurrence, yet adherence is low- particularly among traditionally underserved populations.

Methods

The Carolina Breast Cancer Study oversampled Black and young women (<50 years of age). Participants answered an ET-specific medication adherence questionnaire assessing reasons for non-adherence. We used principal factor analysis to identify latent factors describing ET non-adherence. We then performed multivariable regression to determine clinical and demographic characteristics associated with each ET non-adherence factor.

Results

1,231 women were included in analysis, 59% reported at least one barrier to ET adherence. We identified three

SUBMITTER: Spencer JC 

PROVIDER: S-EPMC7190446 | biostudies-literature | 2020 Apr

REPOSITORIES: biostudies-literature