Automatic reconstruction of the delivered dose of the day using MR-linac treatment log files and online MR imaging.

ABSTRACT:

Background and purpose

Anatomical changes during external beam radiotherapy prevent the accurate delivery of the intended dose distribution. Resolving the delivered dose, which is currently unknown, is crucial to link radiotherapy doses to clinical outcomes and ultimately improve the standard of care.

Material and methods

In this study, we present a dose reconstruction workflow based on data routinely acquired during MR-guided radiotherapy. It employs 3D MR images, 2D cine MR images and treatment machine log files to calculate the delivered dose taking intrafractional motion into account. The developed pipeline was used to measure anatomical changes and assess their dosimetric impact in 89 prostate radiotherapy fractions delivered with a 1.5 T MR-linac at our institute.

R

SUBMITTER: Menten MJ 

PROVIDER: S-EPMC7191265 | biostudies-literature | 2020 Apr

REPOSITORIES: biostudies-literature