Longitudinal Average Glucose Levels and Variance and Risk of Stroke: A Chinese Cohort Study.

ABSTRACT:

Background

Diabetes is a known independent risk factor for stroke. However, whether higher glucose levels (126-139.9 mg/dl) can increase the risk of stroke in people without diabetes is still unknown. Moreover, as a fluctuating parameter, long-term glucose levels may also be related to the risk of stroke outcome. It is important to explore the correlation between long-term average blood glucose, as well as its variability, and stroke.

Methods

We used 40,975 clinical measurements of glucose levels and 367 measurements of glycated hemoglobin A1c levels from 12,321 participants without stroke to examine the relationship between glucose levels and the risk of stroke. Participants were from the Weitang Geriatric Diseases study, including 5,707 men and 6,614 women whose mean age a

SUBMITTER: Peng X 

PROVIDER: S-EPMC7191433 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature