Genomic characterization of Lactobacillus fermentum DSM 20052.

ABSTRACT:

Background

Lactobacillus fermentum, a member of the lactic acid bacteria complex, has recently garnered increased attention due to documented antagonistic properties and interest in assessing the probiotic potential of select strains that may provide human health benefits. Here, we genomically characterize L. fermentum using the type strain DSM 20052 as a canonical representative of this species.

Results

We determined the polished whole genome sequence of this type strain and compared it to 37 available genome sequences within this species. Results reveal genetic diversity across nine clades, with variable content encompassing mobile genetic elements, CRISPR-Cas immune systems and genomic islands, as well as numerous genome rearrangements. Interestingly, we determined a high

SUBMITTER: Brandt K 

PROVIDER: S-EPMC7191730 | biostudies-literature | 2020 Apr

REPOSITORIES: biostudies-literature