Use of endotypes, phenotypes, and inflammatory markers to guide treatment decisions in chronic rhinosinusitis.

ABSTRACT:

Objective

With the advent of new treatment options for Chronic Rhinosinusitis (CRS) comes the ability for physicians to provide more individualized patient care. Physicians are now tasked with identifying who may be the best candidate for a particular therapy. In this review, existing biomarkers and potentially new methods that could guide treatment choices in CRS patients will be discussed.

Data sources

Published literature obtained through PubMed searches.

Study selection

Studies relevant to inflammatory endotypes, phenotypes, and biomarkers in CRS were included.

Results

Currently, there are no clinically validated tools that determine the best therapeutic modality for CRS patients with or without nasal polyps (CRSwNP or CRSsNP). Patients with CRS can be clas

SUBMITTER: Staudacher AG 

PROVIDER: S-EPMC7192133 | biostudies-literature | 2020 Apr

REPOSITORIES: biostudies-literature